What makes a good Omega-3 oil?

Last updated: March 2026 · Reading time: 12 min.

The market for Omega-3 supplements is huge — and confusing. Between cheap capsules from the chemist and premium oils from direct sales companies, there are worlds of difference in quality, bioavailability and purity. But how do you really recognise good Omega-3? Here are the 9 most important criteria you should know before buying.

TL;DR — The key points in brief

1. TOTOX value: The most important freshness indicator

The TOTOX value (Total Oxidation Value) measures how fresh — or how rancid — an Omega-3 oil is. It is calculated from:

TOTOX = 2 × Peroxide Value (PV) + Anisidine Value (AV)

The peroxide value measures early oxidation products, the anisidine value later ones. Why does this matter? Polyunsaturated fatty acids such as EPA and DHA oxidise extremely quickly. A rancid oil can act counter-productively in the body and promote free radicals — the opposite of what you want.

RatingTOTOX ValueMeaning
Excellent< 5Exceptionally fresh
Very good5 – 10High quality, recommended
Acceptable10 – 26GOED/IFOS limit max. 26
Poor> 26Rancid, not recommended

Practical tip

A good Omega-3 oil smells neutral or slightly of the sea — never fishy or rancid. If your oil smells unpleasant, it is likely oxidised.

2. Triglyceride form vs. ethyl ester

This is one of the most important and most underestimated quality differences. Omega-3 comes in various molecular forms:

PropertyNatural Triglyceride (TG)Re-esterified TG (rTG)Ethyl Ester (EE)
Bioavailability100% (reference)~124-134%~73-76%
OriginDirectly from fishReconstitutedSynthetically modified
EPA+DHA concentrationLower (~30%)Very high (>60%)Very high
Gastric toleranceVery goodGoodWorse
PriceModerateHigherCheaper

Conclusion: Natural triglyceride form offers the best combination of bioavailability and tolerability. Ethyl esters are cheaper but are absorbed up to 30% less efficiently. You therefore need more of them for the same effect.

3. EPA/DHA content per daily dose

It is not the amount of "fish oil" that counts, but the actual content of EPA and DHA. Many cheap products contain only 300 mg EPA+DHA per capsule with 1,000 mg fish oil — the rest are other, less valuable fatty acids.

Recommended daily doses according to EFSA:

GoalEPA + DHA per dayEFSA Health Claim
Basic supply250 mgNormal heart function
Brain & eyes250 mg DHANormal brain function, vision
Pregnancy250 mg + 200 mg DHABrain/eye development of foetus
Reducing triglycerides2,000 mgNormal triglyceride levels
Blood pressure3,000 mgNormal blood pressure

Comparison tip

Always compare Omega-3 products based on the cost per gram of EPA+DHA — not per capsule or per millilitre. Only then can you recognise the true value.

4. Purity: Heavy metals, PCBs, dioxins

Fish are at the top of the food chain and can accumulate contaminants. High-quality fish oil supplements must comply with strict limits for:

A good Omega-3 oil is well below the legal limits. Small fish such as sardines and anchovies naturally contain fewer contaminants than large predatory fish such as tuna.

5. Certifications: IFOS and GOED

Not every certification is worth the same:

6. Sustainability

Fish oil production has an ecological footprint. Look out for:

7. Bioavailability and absorption

The best composition is of no use if your body cannot absorb the fatty acids. Important factors:

8. Taste and tolerability

A product is useless if you don't take it regularly. Quality indicators:

9. Value for money

Expensive does not automatically mean better. Always calculate like this:

Cost per gram EPA+DHA = Price per bottle / (EPA+DHA per daily dose × days per bottle)

Factors that justify a higher price:

Factors that do not justify a higher price:

Our product comparisons

We have compared the most popular Omega-3 oils against these criteria:

Eqology vs. Zinzino →  ·  Eqology vs. Norsan →
* Some links are affiliate links. The price does not change for you.

Checklist: What your Omega-3 oil should offer

CriterionMinimumIdeal
TOTOX value< 26< 10, preferably < 5
EPA+DHA per day250 mg1,000-2,000 mg
Molecular formTriglyceride (TG/rTG)
PurityEU limitsIFOS 5-star
SustainabilityMSC or FOS
Antioxidant protectionVitamin EOlive oil polyphenols

Medical disclaimer

This article is for general information purposes only and does not replace medical advice. All health claims are based on EFSA-approved health claims. If you have any doubts about dosage, please consult your doctor.

Frequently Asked Questions

Are Omega-3 capsules or liquid oil better?

Liquid oil is generally cheaper per gram of EPA+DHA and offers higher bioavailability, as it does not need to pass through a gelatine capsule. Capsules are more convenient for travelling.

Why is the TOTOX value so important?

Oxidised (rancid) fish oil can generate free radicals in the body — the opposite of the desired antioxidant effect. A low TOTOX value indicates that the oil is fresh and effective.

Can I overdose on Omega-3?

The EFSA considers daily doses of up to 5,000 mg EPA+DHA to be safe. Therapeutic doses above 3,000 mg should be discussed with a doctor, especially when taking blood-thinning medications.

Further comparison articles on specific products — Eqology, Zinzino and Norsan in direct comparison — can be found in the comparisons overview. All background information on TOTOX values, heavy metals and certifications is provided in the quality overview.